The Biosphere in Montreal is designed from Buckminster Fuller's principles for Geodesic domes. However, these structures originate in nature. Viruses use the principles of 5-fold, 3-fold and 2-fold axes of symmetry. This is probably the most efficient way to pack a genome into a 3-dimensional structure because pentagons do not pixellate. Pixellate means tile into a flat surface. STUDY VIROLOGY WITH VINO to understand this further!
Ironically, when the American Society for Virology met in Montreal, they did not use this structure. Next time in New Orleans!!!